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The method of isolating the occupied ingredient, cocaine hydrochloride, was first perfect in the mid-19th century. Chemists like Albert Niemann in Germany and Paolo Mantegazza in Italy played crucial roles in antediluvian investigation and discovery. By the tardily 1800s, cocaine was being inured to in medical treatments, manifestly as a shire anesthetic, and was equable promoted away pre-eminent figures like Sigmund Freud, who believed it had salubrious potential. No matter how, as its addictive properties became patent, governments began to regulate and done criminalize its run through not later than the inappropriate 20th century.
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